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胰岛素是一种多功能激素,不但在人体的代谢调节中发挥重要作用,对胎儿期及生后的正常生长发育也起了重要的促进作用。胰岛素可能直接或间接通过与促生长素轴的相互作用促进生长。胰岛素的促生长作用主要通过胰岛素受体介导,并通过受体后的信号传导途径实现的。胰岛素分子表面的某些区域或位点对其促生长作用有重要意义。
Insulin is a multifunctional hormone that not only plays an important role in the metabolic regulation of the human body, but also plays an important role in promoting the normal growth and development of the fetus and after birth. Insulin may promote growth either directly or indirectly through interaction with the somatotropin axis. The pro-growth effect of insulin is mainly mediated by the insulin receptor and through the signal transduction pathway after the receptor. Certain regions or sites on the surface of insulin molecules are of great importance for their growth-promoting effect.