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本文报告用外周血淋巴细培胞养,观察21例服醋酸棉酚前和11例服药后染色体的情况。分别按染色体异常与染色单体异常、间隙异常及总异常计算异常细胞数。按群体对比及自身对照分别进行统计学处理,结果P值均在0.02以上。作者认为抗生育剂量的醋酸棉酚对人体淋巴细胞染色体的畸变率无明显影响。
This article reports the use of peripheral blood lymphocyte culture to observe the 21 cases before taking gossypol acetate and 11 cases after taking the chromosomes. According to chromosomal abnormalities and chromatid abnormalities, gap abnormalities and total abnormalities calculated abnormal cell number. By group comparison and self-control were statistically processed, the results were P value of 0.02 or more. The author believes that the anti-fertility dose of gossypol acetate has no significant effect on the rate of chromosome aberration in human lymphocytes.