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目的分析丽珠赛乐治疗新生儿缺氧缺血性脑病的疗效。方法对1998-2001年我院新生儿HIE60例随机分组,全部病例均给予支持、对症综合治疗,其中30例在此基础上加用丽珠赛乐治疗作为观察组,另30例为对照组,将二者进行统计学分析并判断治疗效果。结果观察组与对照组相比,治疗后NBNA评分<35分各为10.296、23.896,x2=0.7981,P>0.05,头颅B超异常率各为20%、50%、x2=5.9341,P<0.05,随访结果预后不良(后遗症加死亡)率各为13.7%、39.3%,x2=4.7846,P<0.05,观察组优于对照组。结论 丽珠赛乐对新生儿HIE治疗有较好效果,在综合治疗基础上加用丽珠赛乐可改善预后。
Objective To analyze the curative effect of CZT on neonatal hypoxic-ischemic encephalopathy. Methods From 1998 to 2001, 60 neonates with HIE in our hospital were randomly divided into two groups. All cases were given supportive and symptomatic comprehensive treatment. Among them, 30 cases were treated with CZL as observation group and the other 30 cases as control group. The two were statistically analyzed and determine the treatment effect. Results Compared with the control group, NBNA score of the observation group after treatment was 10.296, 23.896 and x2 = 0.7981 respectively (P <0.05), and the BNA abnormalities were 20%, 50%, x2 = 5.9341 The follow-up results showed poor prognosis (sequelae plus death) rate of 13.7%, 39.3%, x2 = 4.7846, P <0.05, the observation group was superior to the control group. Conclusions Cabernet Salec on neonatal HIE treatment has a good effect, in the comprehensive treatment based on the use of CZL can improve the prognosis.