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目的 观察还原型谷胱甘肽(TAD)对SAKS肝损伤的疗效。方法 对37例SARS并肝损伤患者予以TAD600mg加入5％葡萄糖250ml中静脉滴入,每日一次,二周为一疗程;治疗前后观察肝功能(ALT、AST、TBIL、GGT)变化及副反应。结果 治疗前后肝功能(ALT、AST、GGT)差异有统计学意义(P<0.01),总有效率81.1％,无副反应发生。结论 TAD在治疗SARS肝脏损伤方面疗效显著且无不良反应。
Objective To observe the effect of reduced glutathione (TAD) on SAKS liver injury. Methods Thirty-seven patients with SARS and liver injury were treated with intravenous infusion of TAD600mg and 250ml of 5% glucose once a day for two weeks. The changes of liver function (ALT, AST, TBIL, GGT) and side effects were observed before and after treatment. Results Before and after treatment, the liver function (ALT, AST, GGT) had statistical significance (P <0.01), the total effective rate was 81.1%, no side effects occurred. Conclusion TAD is effective in treating SARS liver injury with no adverse reactions.