目的探讨血管内介入治疗合并烟雾病的基底动脉尖动脉瘤的安全性和有效性。方法 2006年10月至2013年7月我科经血管内介入治疗7例合并烟雾病的基底动脉尖动脉瘤患者,其中单纯弹簧圈栓塞2例,支架辅助弹簧圈栓塞5例。即刻栓塞结果采用Raymond分级评价,所有患者均获得影像学和临床随访,患者的临床随访结果依据改良Rankin评分(mRS)评价。结果所有患者均成功行介入治疗,无手术相关并发症。术后即刻造影提示:致密栓塞3例,瘤颈残留2例,部分栓塞2例。所有患者均获得影像学随访,平均随访时间(10.4±3.5)个月,6例治愈,1例稳定,支架组患者无支架内再狭窄和血栓形成。临床随访平均(21.1±15.8)个月,所有患者均预后良好(mRS 0~2)。结论血管内介入治疗合并烟雾病的基底动脉尖动脉瘤安全有效,对大型或宽颈动脉瘤,支架植入可能是安全有效的,但仍需长期随访进一步证实。 Objective To investigate the safety and efficacy of endovascular interventional therapy of basilar artery aneurysm with moyamoya disease. Methods From October 2006 to July 2013, 7 patients with basilar artery aneurysm complicated with moyamoya disease were treated with endovascular interventional therapy in our department. Among them, 2 were simple coil embolization and 5 were stent-assisted coil embolization. Immediate embolization results were assessed by Raymond classification. All patients underwent imaging and clinical follow-up. The clinical follow-up results were evaluated according to modified Rankin score (mRS). Results All patients were successfully treated with interventional procedures without complications. Immediate postoperative angiography prompted: dense embolism in 3 cases, 2 cases of residual tumor neck, partial embolism in 2 cases. All patients were followed up for imaging. The mean follow-up time was (10.4 ± 3.5) months. Six patients were cured and one was stable. There was no in-stent restenosis and thrombosis in the stent group. Clinical follow-up averaged (21.1 ± 15.8) months, all patients had a good prognosis (mRS 0 ~ 2). Conclusion Endovascular interventional treatment of aortic aneurysm with moyamoya disease is safe and effective. It may be safe and effective for large or wide-necked aneurysms and stent implantation, but it needs further confirmation in long-term follow-up.