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目的探讨肌萎缩侧索硬化(ALS)合并颈椎病的发病情况、发展速度、症状、体征、肌电图表现、影像学特点分析。方法对43例ALS患者的临床资料进行回顾性分析。结果 ALS在临床上隐袭起病居多,但也可呈亚急性起病。ALS的发展速度可能比以往认为的更快。典型ALS的临床诊断并不困难,但部分患者由于颈椎病的合并存在导致ALS的长期漏诊。EMG检查对ALS的确诊有重要意义。MRI检查对ALS合并颈椎病的诊断有一定的辅助意义。结论 ALS是临床上呈恶性经过的慢性变性疾病。最常见的合并症以及最易导致误诊的是颈椎病。EMG和MRI,检查分别对ALS的诊断有确诊和鉴别诊断意义。
Objective To investigate the incidence of amyotrophic lateral sclerosis (ALS) combined with cervical spondylosis, the development of speed, symptoms, signs, EMG performance, imaging features analysis. Methods The clinical data of 43 patients with ALS were retrospectively analyzed. Results ALS mostly clinically insidious onset, but also showed subacute onset. ALS may develop faster than previously thought. The clinical diagnosis of typical ALS is not difficult, but some patients due to the combination of cervical spondylosis lead to long-term missed diagnosis of ALS. EMG examination of the diagnosis of ALS is of great significance. MRI examination of ALS with cervical spondylosis diagnosis has some secondary meaning. Conclusion ALS is a clinically malignant chronic degenerative disease. The most common complications and the most easily lead to misdiagnosis is cervical spondylosis. EMG and MRI, check the diagnosis of ALS diagnosis and differential diagnosis.