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目的探讨妊娠前空腹血糖(FPG)、体重指数(B M I)对妊娠糖尿病(GDM)的预测临床价值。方法选取2014年1月至2015年1月在我院进行生育前检查且查后4个月受孕的80例妇女检测资料进行研究,将妊娠期糖尿病患者划分为实验组(29例),其他51例非妊娠期糖尿病对象为比照组。统计不同组别孕妇的妊娠前空腹血糖、体重指数等数据,分析两组妊娠前空腹血糖、体重指数与妊娠期糖尿病的相关性。结果实验组的孕前空腹血糖、体重指数均高于比照组(P<0.05)。实验组的孕23-27周OGTT的FPG、1h和2h血糖均较对照组的高,多元Logistic回归分析显示,孕前4个月内FPG、BMI与GDM的发生密切相关(P<0.05),随着孕前FPG和BMI的增加,孕后患GDM的概率升高。结论妊娠前对空腹血糖、体重的检查对预测孕后糖尿病发病情况诊断具有一定的指导价值。
Objective To investigate the clinical value of fasting blood glucose (FPG) and body mass index (BMI) in predicting gestational diabetes mellitus (GDM) before pregnancy. Methods A total of 80 women who underwent prenatal examination from January 2014 to January 2015 in our hospital who had conception before pregnancy and 4 months after pregnancy were selected to study. The gestational diabetes patients were divided into experimental group (n = 29) and other 51 Cases of non-gestational diabetic subjects for the control group. Statistics of different groups of pregnant women before pregnancy, fasting blood glucose, body mass index and other data were analyzed before pregnancy, fasting blood glucose, body mass index and gestational diabetes mellitus. Results The fasting blood glucose and body mass index of the experimental group before pregnancy were higher than those of the control group (P <0.05). The FPG, 1h and 2h blood glucose levels of OGTT in experimental group were higher than those in control group at 23-27 weeks of gestation. Multivariate logistic regression analysis showed that there was a close correlation between FPG, BMI and GDM (P <0.05) Before pregnancy FPG and BMI increase, the risk of pregnancy with GDM increased. Conclusion The examination of fasting blood glucose and body weight before pregnancy has certain guiding value in the prediction of the incidence of diabetes after pregnancy.