庆大霉素疗效较好,无过敏性,临床应用广泛,但其安全范围却较狭窄,容易引起耳肾毒性。为此,研究和寻找最佳给药方案引起了医药人员的极大重视。国外七十年代、国内八十年代以来,不断有人进行庆大霉素药物动力学研究和给药方案的设计,上海第六人民医院药剂科实验室通过五名正 Gentamicin has a good curative effect, no allergy and a wide range of clinical applications, but its safety range is rather narrow, which can easily cause ototoxicity. To this end, research and find the best drug program attracted great attention of medical personnel. Seventies abroad, the domestic since the eighties, some people continue gentamicin pharmacokinetic studies and dosing program design, Shanghai Sixth People’s Hospital Pharmacy Laboratory through the five positive