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体外已证实各种重组人造血生长因子(HGFS)联合协同扩增造血干细胞。粒细胞集落刺激因子(RHG—SCF)或粒一单细胞集落刺激因子(rhGM—CSF)已用于肿瘤病人化疗后粒细胞减少及造血干细胞移植后的中性粒细胞恢复。但HGFS对造血干/祖细胞在体内的扩增作用研究不多。我们在己建
In vitro, various recombinant human hematopoietic growth factors (HGFS) have been demonstrated to synergistically amplify hematopoietic stem cells. Granulocyte colony stimulating factor (RHG-SCF) or granulocyte-single-cell colony-stimulating factor (rhGM-CSF) have been used to treat neutropenia in patients with neoplasm after chemotherapy and neutrophil recovery after hematopoietic stem cell transplantation. However, the role of HGFS in the proliferation of hematopoietic stem / progenitor cells in vivo is not much. We have built