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目的探讨女性泌尿生殖道感染患者中支原体的感染状况及其对不同药物的敏感性分析。方法对470例标本进行支原体培养,并对支原体阳性标本进行9种抗生素药敏试验。结果 470例患者中,支原体培养阳性185例,检出率为39.36%,其中解脲支原体(Uu)阳性139例(75.14%),人型支原体(Mh)阳性13例(7.03%),Uu+Mh阳性33例(17.84%)。Uu感染对克拉霉素、阿奇霉素、美满霉素和强力霉素较为敏感;Mh及Uu+Mh感染均对美满霉素和强力霉素较为敏感。结论长沙地区泌尿生殖道支原体感染患者中以Uu为主,美满霉素和强力霉素可以作为泌尿生殖道支原体感染治疗的首选药物。
Objective To investigate the prevalence of Mycoplasma in women with genitourinary tract infection and its sensitivity to different drugs. Methods 470 cases of mycoplasma culture, and mycoplasma positive specimens for 9 kinds of antibiotic susceptibility testing. Results Of the 470 patients, 185 were positive for mycoplasma and the detection rate was 39.36%. Among them, 139 (75.14%) were positive for Uu, 13 (7.03%) were positive for Mh, Uu + Mh positive in 33 cases (17.84%). Uu infection was more sensitive to clarithromycin, azithromycin, minocycline and doxycycline; Mh and Uu + Mh infections were sensitive to minocycline and doxycycline. Conclusion Uu is the main source of genitourinary tract mycoplasma infection in Changsha. Minocycline and doxycycline can be used as the drug of choice for the treatment of genitourinary tract mycoplasma infection.