论文部分内容阅读
目的 :探讨博宁联合153Sm EDTMP治疗恶性肿瘤多发骨转移的临床疗效。方法 :32例恶性肿瘤多发骨转移患者随机分为 2组 ,每组 16例 ,分别接受153Sm EDTMP单独或与博宁联合治疗。结果 :联合组疼痛总缓解率 (CR +PR)为 93 8% ,单用组为 62 5% ,骨病灶控制总有效率 (CR +PR)联合组56 3% ,单用组为 18 8% ,联合组疗效优于单用组 (P <0 0 5) ,两组均无严重的毒副作用。结论 :博宁联合153Sm EDTMP是目前治疗晚期恶性肿瘤多发骨转移的优选方案
Objective : To explore the clinical efficacy of Bonin combined with 153Sm EDTMP in the treatment of multiple bone metastases of malignant tumors. METHODS: Thirty-two patients with multiple bone metastases of malignant tumors were randomly divided into 2 groups, 16 in each group. They were treated with 153Sm EDTMP alone or in combination with Bonin. Results: The total pain remission rate (CR +PR) was 93 8% in the combined group, 62 5% in the single-use group, 56 3% in the combined control group of bone lesions (CR +PR), and 18 8% in the single-use group. The efficacy of the combination group was better than that of the single-use group (P <0 05), and there were no serious side effects in the two groups. Conclusion : The combination of Boning and 153Sm EDTMP is the optimal treatment for multiple bone metastases in advanced malignant tumors.