论文部分内容阅读
在造血系统恶性疾病诊断时等臂染色体的报道很少,通常作为一个复杂克隆的一部分.本文作者报告了5例诊断为急性淋巴细胞白血病(ALL)时伴i(9q)的病例,其中有一例为单一的核型异常.5例病人,男性2例,女性3例,按FAB标准均诊断为ALL.L1型4例,L2型1例.免疫表型:C-ALL2例,Pre-B2例,T-ALL1例.临床特征:年龄>10岁3例,脾脏及淋巴结肿大4例,无1例肝脏肿大,白细胞>10×10~9/L2例,外周血原始细胞>90%者3例,5例骨髓原始细胞均>70%.有两例病
In the diagnosis of hematopoietic malignancy, there are few reports of isochrons, usually as part of a complex clone.The authors report five cases of i (9q) diagnosed with acute lymphoblastic leukemia (ALL), of which one case As a single karyotypic abnormalities in 5 patients, 2 males and 3 females, according to FAB criteria were diagnosed as ALL.L1 in 4 cases, L2 in 1. Immunophenotype: C-ALL in 2 cases, Pre-B2 cases , T-ALL 1 cases.Clinical features: 3 patients aged> 10 years old, 4 cases of spleen and lymph node enlargement, no liver enlargement, white blood cells> 10 × 10 ~ 9 / L2 cases, peripheral blood blasts> 90% 3 cases, 5 cases of bone marrow blast cells were> 70%. There are two cases of disease