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对368例重型病毒性肝炎患者医院感染进行了调查分析。结果显示:重型病毒性肝炎患者的医院感染率为47.8%;感染部位以腹膜腔最为多见,占49.4%,其次为肠道,占17.4%;感染病原菌以革兰氏阴性菌为主,占69.9%;医院感染与侵入性医疗操作有密切关系;重型病毒性肝炎合并医院感染组的病死率明显高于无合并医院感染组(X2=16.99,P<0.001)。结果提示:加强重型病毒性肝炎患者医院感染的预防和监控有十分重要的意义。
The hospital infection of 368 patients with severe viral hepatitis were investigated. The results showed that the rate of nosocomial infection in patients with severe viral hepatitis was 47.8%. The most common sites of infection were peritoneal cavity, accounting for 49.4%, followed by intestinal tract, accounting for 17.4%. The infected pathogens were Gram Negative bacteria, accounting for 69.9%; hospital infection and invasive medical operations are closely related; severe viral hepatitis with hospital infection group mortality was significantly higher than without hospital infection (X2 = 16.99, P < 0.001). The results suggest that: to strengthen the prevention and surveillance of nosocomial infections in patients with severe viral hepatitis is of great significance.