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目的探讨动态脉压(PP)和脉压指数(PPI)与脑卒中发生的关系。方法利用动态血压监测(ABPM)测定242例脑出血和208例脑梗死患者24 h ABPM 变化,并与280例体检人员的 ABPM 做对比。结果脑出血、脑梗死组的24 h 平均 PP(24h PP)、24 h 平均 PPI(24 h PPI)与对照组比较差异均有非常显著性(P<0.01)。脑出血组和脑梗死组24 h PP 的最大分布区域均在60～89 mmHg,分别占64.5%和64.4%;对照组24 h PP 最大分布区域在40～69 mmHg,占80.4%;脑出血组和脑梗死组24 hPPI 的最大分布区域均在0.40～0.49,而对照组24 h PPI 在<0.40。而且,三组24 h PP、24 h PPI 随年龄增长呈增加趋势。结论脑卒中病人的 PP 与 PPI 较同年龄无脑卒中者明显增加,PP、PPI 增加与脑卒中的发生有关,是脑卒中的重要危险因素之一。
Objective To investigate the relationship between dynamic pulse pressure (PP) and pulse pressure index (PPI) and stroke. Methods ABPM was used to measure the change of ABPM in 242 patients with cerebral hemorrhage and 208 patients with cerebral infarction at 24 h, and compared with that of 280 patients with ABPM. Results The difference of 24 h PPI (24 h PPI) and 24 h PPI (24 h PPI) in cerebral hemorrhage and cerebral infarction group was significant (P <0.01). The maximum distribution area of PP in cerebral hemorrhage group and cerebral infarction group was 60-89 mmHg at 24 h, accounting for 64.5% and 64.4% respectively. The maximum distribution area of PP in 24 h in control group was 40-69 mmHg, accounting for 80.4% And cerebral infarction group 24 hPPI maximum distribution of 0.40 to 0.49, while the control group 24 h PPI <0.40. Moreover, the PPI of 24 h and 24 h of three groups increased with age. Conclusion Compared with the same age, the PP and PPI of stroke patients are obviously increased. The increase of PP and PPI is related to the occurrence of stroke, which is one of the important risk factors of stroke.