50例患者均有肛周尖锐湿疣,男34例,女16例,年龄16~36岁,其中20~30岁占90%左右,病程最长2年,最短30d,有不洁性交史者45人,50例患者均为1~3次发病。皮损部位为单纯分布肛门18例,分布生殖器32例,皮损形态呈菜花样及豆状样为多,或癣样,最大面积3cm×4cm。病理检查均符合尖锐湿疣。治疗方法:清洗肛门会阴部位,皮肤常规消毒,用1%利多卡因局部麻醉或点状麻醉,用CO_2激光刀切除肛门周围及会阴部位的尖锐湿疣。同时将疾病组织气化、碳化。术后肌注抗病毒药物或抗生素类,防止创面感染。结果:6~8个月复发23例,1~2年复发3例。 50 patients were perianal genital warts, 34 males and 16 females, aged 16 to 36 years, of which 20 to 30 years of age accounted for about 90%, the longest duration of 2 years, the shortest 30d, have unclean sexual intercourse 45 People, 50 patients were 1 to 3 times the incidence. The lesion site was a simple distribution of anus in 18 cases, 32 cases of genital distribution, the lesion was cauliflower-like and bean-like or more, or ringworm, the largest area of ​​3cm × 4cm. Pathological examination are consistent with genital warts. Treatment: Clean the perineal anus, skin routine disinfection, with 1% lidocaine local anesthesia or punctate anesthesia, with CO_2 laser knife removal around the anus and perineal genital warts. At the same time the disease tissue gasification, carbonization. Postoperative intramuscular antiviral drugs or antibiotics to prevent wound infection. Results: 23 cases recurred in 6 ~ 8 months and 3 cases recurred in 1 ~ 2 years.