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在236例无选择的一般不育妇女中,前瞻性研究了氯菧酚胺(CC)试验筛查反应与患者年龄、不育病因及远期妊娠率的关系。 受试者平均年龄34±0.2岁,原发不育140例,继发不育96例。其中12例有卵巢手术史但无切除卵巢者。全组在初诊后2个月内行CC试验,即于孕酮撤退出血第5天(D_5)起口服CC 100mg/d共5天。D_3及D_(10)各取血测FSH浓度。经与WHO第二国际标准(78/549)校对后以FSH>10IU/L,定为异常反应。全组皆行全面不育检查及适当治疗,并至少随诊1年以了解最后诊断及妊娠情况。
In a prospective study of 236 infertile women of general infertility, we prospectively examined the relationship between the screening response of the clopidogrel (CC) test and the patient’s age, causes of infertility and long-term pregnancy rates. The average age of subjects 34 ± 0.2 years, 140 cases of primary infertility, 96 cases of secondary infertility. Of these, 12 had ovarian surgery but had no ovariectomy. The whole group underwent CC test within 2 months after first visit, ie CC 100 mg / d for 5 days after the progesterone withdrawal bleeding day 5 (D_5). D_3 and D_ (10) take the blood test FSH concentration. An FSH> 10 IU / L after proofreading with WHO’s second international standard (78/549) was considered an abnormal reaction. All patients underwent comprehensive infertility examination and appropriate treatment, and at least 1 year follow-up to understand the final diagnosis and pregnancy.