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目的:探讨冠状动脉病变范围及狭窄程度与心脏功能的关系。方法:选择性冠状动脉造影387例,冠状动脉造影证实冠心病患者252例,按病变范围、狭窄程度分组,术前行心脏超声检查,对比分析冠状动脉病变范围及狭窄程度与功能的关系。结果:冠状动脉轻、中度狭窄、1支病变时,左室收缩功能改变不明显,舒张功能出现减退(P<0.05或P<0.01)。冠状动脉重度狭窄、完全闭塞时,舒张功能明显减退(P<0.01),收缩功能与受累血管数量、病变程度有明显相关性。结论:冠状动脉病变对心脏的功能有一定影响,冠心病患者心脏舒张功能减退先于收缩功能。
Objective: To investigate the relationship between the extent of coronary lesion and the degree of stenosis and cardiac function. Methods: Selective coronary angiography was performed in 387 patients. Coronary angiography was performed in 252 patients with coronary heart disease. The extent of the disease and the degree of stenosis were determined. The echocardiographic examination was performed preoperatively to analyze the relationship between the extent of coronary artery stenosis and the degree of stenosis. Results: There was no significant change in left ventricular systolic function and diastolic function (P <0.05 or P <0.01) in patients with mild and moderate coronary artery stenosis. Severe coronary stenosis, complete occlusion, diastolic function was significantly reduced (P <0.01), systolic function and the number of affected vessels, the degree of lesions were significantly correlated. Conclusion: Coronary artery disease has a certain impact on the function of the heart, and diastolic dysfunction precedes contraction in patients with coronary heart disease.