有三分之一以上系统性红斑狼疮(SLE)的病人出现神经症状,包括:癫痫发作,精神改变,偏瘫,颅神经功能障碍和神经病。有很大部分的SLE患者出现眼外肌障碍。其中有许多患者亦出现视网膜上局限性血管性病损。有视乳头水肿而无视力丧失者虽常提到,但失明则极罕见。新近报告的一组150例SLE患者中只有3例有进行性失明伴有视神经萎缩。 Neurological symptoms occur in more than one third of patients with systemic lupus erythematosus (SLE), including seizures, psychiatric changes, hemiplegia, cranial nerve dysfunction and neuropathy. A large proportion of patients with SLE have ocular disorders. Many of these patients also have localized retinal vascular lesions. Although there are often mentioned papilledema without loss of vision, blindness is extremely rare. Only three of the newly reported 150 patients with SLE recently reported progressive blindness associated with optic atrophy.