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一、前言地方性克汀病,是发生在较严重的地方性甲状腺肿流行区的一种常见地方病。仅据我国北方16省市区的不完全统计,就有比较严重的典型患者17万人之多,占北方病区人口的1.1‰,不少重病区的患病率高达10‰乃至于100‰以上。因此地方性克汀病是一种危害人民深重的地方病。自 Plater 于1614年首次报告以来,对地方性克汀病的研究已有360多年的历史。近年来国内外学者对地方性克汀病的病因和发病机理等的研究越来越深入,并且积累相当丰富的防治经验,逐渐地打破了认为地方性克汀病是“不治之症”的观点,也修正了地方性克汀病给机体造成的损伤是“不可逆性”的概念。
I. INTRODUCTION Endemic cretinism is a common endemic disease that occurs in the more endemic endemic goiter areas. According to the incomplete statistics of 16 provinces and municipalities in northern China, there are as many as 170,000 typical patients, accounting for 1.1 ‰ of the northern ward population. The prevalence of many seriously ill areas is as high as 10 ‰ or even 100 ‰ the above. Therefore, endemic cretinism is a endemic disease that endangers the people. Since Plater’s first report in 1614, the study of endemic cretinism has been around for more than 360 years. In recent years, domestic and foreign scholars on the etiology and pathogenesis of endemic cretinism more and more in-depth, and the accumulation of considerable experience in prevention and treatment, and gradually break the view that endemic cretinism is “incurable disease” point of view , And also amended the notion that the damage caused by endemic cretinism to the body is “irreversible”.