目的:优选一个合适剂量,使吗啡对家兔呼吸中枢既能起到抑制作用,又能节约吗啡用量。方法:0.618法。过程:用1％的浓度,在1—2ml/kg范围内优选。第一试验点(2—1)×0.618+1=1.62ml 出现明显呼吸抑制现象第二试验点(2+1)-1.62=1.38ml 出现明显呼吸抑制现象 OBJECTIVE: To optimize a suitable dose to make morphine not only inhibit the respiratory center of rabbits, but also save the dosage of morphine. Method: 0.618 method. Procedure: 1% concentration is preferred in the range of 1-2 ml / kg. The first test point (2-1) × 0.618 +1 = 1.62ml obvious respiratory depression phenomenon The second test point (2 +1) -1.62 = 1.38ml obvious respiratory depression