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RU486是一种合成的19-去甲类固醇,具强有力的抗孕酮活性,对早孕有堕胎作用。欧美早些时候研究其口服给药流产成功率差别很大,从10%～94%。本研究是单纯口服大剂量的(600mg)RU486,试图提高其堕胎率。本研究包括50例病人,年龄≥18岁,身体健康,月经规律(28±3天),停经≤49天,均测定了血清β-hCG。凡有先兆流产、先前曾试做过流产、宫颈机能不全、双合诊查子宫大于7周妊娠或
RU486 is a synthetic 19-nor-steroid with potent anti-progesterone activity and abortions for early pregnancy. Earlier in Europe and the United States to study the success rate of oral administration of abortion varies widely, from 10% to 94%. This study is a simple oral high dose (600mg) RU486, trying to increase its abortion rate. This study included 50 patients, aged> 18 years, healthy, menstruation (28 ± 3 days), menopause ≤ 49 days, were measured serum β-hCG. Where threatened abortion, had previously tried abortion, cervical insufficiency, double check the uterus for more than 7 weeks of pregnancy or