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本文报道慢性肾炎肾功能不全68例,其中26例出现肾原性抽搐,占38.2％。严重的神经症状是该病早期病情急骤进展较常见的征象和并发症,肌阵挛、肌抽搐、癫痫样发作等尿毒症脑病表现者占42.3％,均与肾功能损害的程度相平行。其中19/26例发生在1周以内,88.4％有明显的意识障碍。4例于1周内死亡。脑病和抽搐是二种主要神经系统并发症。脑病BUN临界值是21.4mmol/L,发生抽搐的临界值是25mmol/L,认为BUN增高和低钙血症、高血压是抽搐的主要原因。小于7岁和CRF一年以上者发生率增高。
This article reports 68 cases of chronic renal failure renal insufficiency, of which 26 cases of renal convulsions, accounting for 38.2%. Severe neurological symptoms are the most common signs and complications of rapid progression of the disease in the early stage of the disease, with 42.3% of uremic encephalopathy manifested as myoclonus, muscle twitch and epileptic seizures, all of which are parallel to the extent of renal dysfunction. 19/26 cases occurred within 1 week, 88.4% had obvious disturbance of consciousness. 4 patients died within 1 week. Encephalopathy and convulsions are two major neurological complications. Encephalopathy BUN threshold is 21.4mmol / L, the threshold for occurrence of convulsions is 25mmol / L, that elevated BUN and hypocalcemia, hypertension is the main reason for convulsions. Less than 7 years of age and CRF increased more than one year.