细胞凋亡是维持细胞正常新陈代谢的重要功能和特性,细胞凋亡抑制能增加肿瘤细胞的存活时间,免疫监视逃逸。因此,细胞的凋亡抑制和过度增殖是肿瘤发生的重要机制。细胞凋亡异常源自细胞凋亡控制机制的改变,即凋亡抑制基因和凋亡活化基因的异常,研究已证明Caspase在细胞凋亡的执 Apoptosis is to maintain the normal metabolism of cells important functions and characteristics, apoptosis can increase the survival of tumor cells, immune surveillance escape. Therefore, apoptosis and hyperproliferation of cells is an important mechanism of tumorigenesis. Abnormal apoptosis arises from changes in the mechanism of apoptosis control, that is, abnormalities of apoptosis-suppressing genes and apoptosis-activating genes. Studies have demonstrated that Caspase is involved in apoptosis