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本研究通过检测１４例胆囊结石病人胆囊切除术前后胃内胆酸含量，发现其十二指肠胃反流（ＤＧＲ）发生率分别为８５７１％和１００％，正常对照组为２１４３％，差异显著（Ｐ＜０．０１）；同时检测手术前后血清胃泌素分别为１６２９５±５６２８ｐｇ／ｍｌ、１４７．８７±３７．６１ｐｇ／ｍｌ，均显著高于对照组１０５０５±２６．８５ｐｇ／ｍｌ，而基础胃酸排量、最高胃酸排量与对照组比较无明显差异。作者分析，此种病人胃肠道激素改变是影响Ｏｄｄｉ括约肌运动状态和胃－幽门－十二指肠协调运动的主要因素，亦即是引起ＤＧＲ的基本原因，也是胆囊切除术后综合征的原因之一，其治疗可选用促胃肠动力药物。
In this study, 14 cases of cholecystolithiasis by cholecystectomy before and after cholecystectomy in the stomach and found that the duodenal regurgitation (DGR) rates were 85.71% and 100%, respectively, the normal control group was 21.43 %, The difference was significant (P <0.01). The serum gastrin levels before and after the operation were 16295 ± 5628pg / ml and 147.87 ± 37.61pg / ml respectively, which were significantly higher than those in the control group 05 ± 26.85pg / ml, while the basic gastric acid secretion, the highest gastric acid output compared with the control group no significant difference. The authors analyzed that such gastrointestinal tract changes in patients with gastrointestinal hormones affect sphincter movement and gastric - pylorus - duodenal coordination of movement of the main factors that cause DGR is the basic reason is also the cause of cholecystectomy syndrome One of its treatment can be used to promote gastrointestinal motility drugs.