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目的探讨有创性主动脉脉压、增强指数和脉搏波传导速度之间相关性及临床意义。方法选择住院行诊断性冠脉造影患者37例,年龄(62.53±22.32)岁,男24例、女13例。其中冠心病18例,高血压11例,对照组(无危险因素)8例。冠脉造影结束后同步记录升主动脉与股动脉压力波形,测量并分析外周及中心动脉血压,计算增强指数、脉搏波传导速度。结果1)PWV与PP正相关(r=0.77,P<0.01);2)PWV与AI之间关系复杂;与A型不相关(r=0.149,P=0.53),与C/D亚型存在等级相关(P<0.05);3)PWV>10 m/s,PP>60 mmHg均对高血压、动脉硬化和冠心病有预测价值。结论PWV、PP、AI对动脉硬化和粥样硬化等有一定预测价值,以PWV更优,3个指标结合应用能为动脉病变提供更多诊断信息,有助于心血管病早期预防、危险分层和疗效评估。
Objective To investigate the correlation and clinical significance of invasive aortic pulse pressure, enhancement index and pulse wave velocity. Methods Thirty-seven patients with diagnostic coronary angiography in hospital were enrolled in this study. Their ages (62.53 ± 22.32) years, 24 males and 13 females. Of which 18 cases of coronary heart disease, hypertension in 11 cases, control group (no risk factors) in 8 cases. After the coronary angiography, the ascending aorta and femoral artery pressure waveforms were recorded synchronously. The peripheral and central arterial blood pressure were measured and analyzed. The enhancement index and pulse wave velocity were calculated. Results PWV was positively correlated with PP (r = 0.77, P <0.01). 2) The relationship between PWV and AI was complicated. There was no correlation between PWV and AI (r = 0.149, P = 0.53) (P <0.05). 3) PWV> 10 m / s and PP> 60 mmHg all have predictive value for hypertension, arteriosclerosis and coronary heart disease. Conclusions PWV, PP and AI have some predictive value for atherosclerosis and atherosclerosis. PWV is superior and combined with 3 indexes can provide more diagnostic information for arterial disease, which is helpful to early prevention of cardiovascular disease, risk score Layer and efficacy evaluation.