论文部分内容阅读
目的探讨脑血管支架置入血管成形术的安全性和术后不良事件的影响因素。方法选择2005年1月～2010年12月行脑血管支架置入治疗的患者893例,分别在术前1 h、术后24 h及术后30 d进行神经功能评估。结果脑血管支架置入的成功率为99.6%。住院期间,5例(0.6%)发生血管性死亡、11例(1.2%)发生卒中;随访30 d,发生卒中和死亡共19例(2.1%)。年龄>80岁及有症状者发生卒中和死亡的比例明显高于年龄<80岁和无症状者(4.3%对1.1%,P<0.05;12.5%对2.0%,P<0.05),而有手术风险及伴有内科疾病并不增加术后卒中或死亡的风险。结论血管内支架置入术是安全的,术后不良事件的风险与伴有神经缺损症状和年龄相关,而与手术高危因素或内科疾病无明确相关。
Objective To investigate the safety of angioplasty with cerebral vascular stenting and the influencing factors of postoperative adverse events. Methods A total of 893 patients underwent stenting of cerebrovascular stents from January 2005 to December 2010 were enrolled. Neurological evaluation was performed at 1 h before operation, 24 h after operation and 30 d after operation. Results The success rate of cerebrovascular stenting was 99.6%. During hospitalization, vascular death occurred in 5 patients (0.6%) and stroke in 11 patients (1.2%). Stroke and death occurred in 19 patients (2.1%) at 30 days of follow-up. The proportion of stroke and death at age> 80 years and those with symptoms was significantly higher than those at <80 years of age and asymptomatic (4.3% vs 1.1%, P <0.05; 12.5% vs. 2.0%, P <0.05) Risks associated with medical conditions do not increase the risk of postoperative stroke or death. Conclusion Endovascular stenting is safe and the risk of postoperative adverse events is related to the symptoms and age associated with neurological deficits. However, it is not related to the risk factors of surgery or medical diseases.