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目的探讨尿路感染(urinary tract infection,UTI)常见致病菌的分布及其尿液pH值的特征。方法采集606例本院UTI细菌培养阳性结果及感染后尿pH值数据,分析致病菌的分布,按照菌属将主要致病菌分为3组,统计分析不同菌属感染尿pH值的差异。结果UTI致病菌总例数606例,埃希菌属186例(30.7%),感染尿液pH值集中地分布于6.21～6.33;念珠菌属152例(25.1%),尿pH值集中分布于5.81～5.95;肠球菌属86例(14.2%),感染尿pH值集中分布于6.10～6.28。比较3组尿液pH值发现念珠菌属感染的尿pH值明显偏酸(P<0.05)。结论UTI尿pH值发生改变,不同的UTI致病菌所对应的尿pH值不同且差别较大,通过调整尿pH值能更有效地抑制致病菌的生长,提高抗菌药物的药物效应。
Objective To investigate the distribution of common pathogenic bacteria in urinary tract infection (UTI) and the characteristics of urine pH value. Methods The positive results of bacterial culture of UTI in our hospital and urinary pH value data after infection were collected from 606 patients in our hospital. The distribution of pathogens was analyzed. The main pathogenic bacteria were divided into 3 groups according to genus, and the differences in urinary pH values . Results The total number of UTI pathogens was 606 and that of Ehrlichia was 186 (30.7%). The urinary pH was concentrated in 6.21 ~ 6.33 and 152 (25.1%) were Candida spp. In 5.81 ~ 5.95; Enterococcus 86 cases (14.2%), the concentration of urinary infection concentrated in the distribution of 6.10 ~ 6.28. The urinary pH of three groups was significantly higher than that of the urine of Candida (P <0.05). Conclusions UTI urine pH value changes, different UTI pathogens corresponding to different pH values and differences between the larger, by adjusting the urine pH value more effectively inhibit the growth of pathogenic bacteria and improve the antimicrobial drug effect.