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目的:观察氯胺酮复合七氟醚用于小儿静脉全麻的临床效果。方法:将择期实施手术治疗的65例患儿随机分为两组,A组30例单纯给予氯胺酮麻醉维持,B组35例给予氯胺酮复合七氟醚麻醉维持,观察两组麻醉效果。结果:B组麻醉前、术中心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO2)比较差异不显著(P>0.05);A组术中上述指标与麻醉前比较差异显著(P<0.05);B组氯胺酮使用剂量、意识恢复时间、患者术中躁动率、呼吸抑制率均优于A组(P<0.05)。结论:氯胺酮复合七氟醚用于小儿静脉全麻,可减少氯胺酮用量,维持血流动力学稳定性,使患儿安全度过手术期。
Objective: To observe the clinical effect of ketamine combined sevoflurane for general anesthesia in children. Methods: Sixty-five children who underwent elective surgery were randomly divided into two groups. A group of 30 patients were treated with ketamine alone and 35 patients of group B were given ketamine combined sevoflurane anesthesia. The anesthetic effects were observed. Results: There were no significant differences in HR, MAP and SpO2 between group A and group B before anesthesia (P> 0.05). The above indexes in group A were significantly different from those before anesthesia (P <0.05). The dosage of ketamine, the recovery time of consciousness, intraoperative agitation rate and respiration inhibition rate in group B were better than those in group A (P <0.05). Conclusion: Ketamine combined with sevoflurane for pediatric intravenous anesthesia can reduce the dosage of ketamine and maintain hemodynamic stability, so that children can safely pass the operation.