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目的：观察蛛网膜下腔出血（ＳＡＨ）后迟发性脑血管痉挛（ＤＣＶＳ）的发生与免疫复合物（ＩＣ）及补体成分（Ｃ３、Ｃ４）变化的关系。方法：采用比浊法，单向免疫扩散法，对１３７例ＳＡＨ患者于发病１周内、第２周、第３周进行血清ＩＣ、Ｃ３、Ｃ４动态检测，根据临床症状、辅助检查结果分为ＤＣＶＳ组与无ＤＣＶＳ组，比较两组间不同病程免疫指标的变化。结果：发现ＤＣＶＳ组于发病１周内ＩＣ、Ｃ３、Ｃ４水平高于无ＤＣＶＳ组，并持续２周，后随临床症状好转逐步降至正常范围。结论：动态观察ＩＣ及补体成分，可作为预测ＤＣＶＳ的可能性和估价病情危重程度的指标，同时也为临床应用免疫抑制剂预防ＤＣＶＳ提供依据。
Objective: To observe the relationship between the occurrence of delayed cerebral vasospasm (DCVS) and immune complex (IC) and complement components (C3 and C4) after subarachnoid hemorrhage (SAH). Methods: Serum IC, C3 and C4 were detected in 137 patients with SAH within 1 week, 2 weeks and 3 weeks after onset by turbidimetry and unidirectional immunodiffusion. According to the clinical symptoms and the results of the auxiliary examination DCVS group and no DCVS group. The changes of immune indexes in different course of the two groups were compared. Results: The levels of IC, C3 and C4 in DCVS group were significantly higher than those in DCVS group within 1 week after the onset of disease, and continued for 2 weeks. However, they gradually dropped to the normal range with the improvement of clinical symptoms. Conclusion: The dynamic observation of IC and complement components can be used as an index for predicting the possibility of DCVS and assessing the severity of illness. It also provides a basis for the clinical application of immunosuppressive agents in the prevention of DCVS.