论文部分内容阅读
目的:研究玉竹叶乙醇提取物乙酸乙酯和正丁醇分离部位的化学成分。方法:采用十八烷基键合硅胶柱色谱和制备液相色谱等手段进行化学成分分离,运用理化性质和波谱数据(MS,1H-NMR,13C-NMR,HMBC等)鉴定化合物结构。结果:从玉竹叶乙醇提取物乙酸乙酯和正丁醇部位中分离得到10个化合物,分别鉴定为香草酸(1),反式-对羟基桂皮酸(2),顺式-3-己烯醇-β-D-葡萄糖苷(3),N-反式-对羟基苯乙基香豆酰胺(4),N-反式-对羟基苯乙基阿魏酰胺(5),芹菜素(6),金圣草黄素(7),腺苷(8),肥皂草苷(9)和异牡荆素(10)。结论:所有化合物均为首次从玉竹叶部位中分离得到,其中化合物1~4,6,8,10为首次从黄精属植物中分离得到。
Objective: To study the chemical constituents from the ethyl acetate and n-butanol fractions of the ethanol extract of Polygonatum pubes. Methods: The chemical constituents were separated by octadecyl-bonded silica gel column chromatography and preparative liquid chromatography. The structures of the compounds were identified by physicochemical properties and spectral data (MS, 1H-NMR, 13C-NMR, HMBC, etc.) Results: Ten compounds were isolated from the ethyl acetate and n-butanol fractions of Polygonatum odoratum and identified as vanillic acid (1), trans-p-hydroxycinnamic acid (2) (3), N-trans-p-hydroxyphenethylcoumarol (4), N-trans-p-hydroxyphenethylferunamide (5), apigenin (7), Adenosine (8), Saponin (9) and Isovitexin (10). Conclusion: All the compounds were isolated from the leaves of Polygonatum for the first time. Compounds 1 ~ 4, 6, 8 and 10 were isolated from Polygonatum for the first time.