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本文用生物素—链霉亲和素酶联免疫吸附试验(BSA)对203例血清CA19-9水平进行定量测定。结果显示,在32例胰腺癌组为826±411U/ml,40例肝癌组为107±46.5U/ml,与76例正常人对照组21.2±9.24U/ml比较均有明显差异(P<0.05),以胰腺癌组升高最显著。在39例胃癌组为25.4±11.0U/ml,与正常对照组比较均无明显差异(P>0.05)。27例胰腺癌病人术前为910±452U/ml,术后为187±89.0U/ml,血清CA19-9水平明显下降(P<0.05)。血清CA19-9水平分析对胰腺癌的鉴别诊断、疗效观察及预后评估有较高价值。
In this study, 203 serum CA19-9 levels were quantitatively determined by biotin-streptavidin enzyme-linked immunosorbent assay (BSA). The results showed that 32 cases of pancreatic cancer group were 826±411 U/ml, and 40 cases of liver cancer group were 107±46.5 U/ml, which were significantly different from the 76 normal control group of 21.2±9.24 U/ml. (P < 0.05), the most significant increase in the pancreatic cancer group. In the 39 cases of gastric cancer was 25.4 ± 11.0U/ml, there was no significant difference compared with the normal control group (P> 0.05). Twenty-seven patients with pancreatic cancer were preoperatively 910±452 U/ml, postoperatively 187±89.0 U/ml, serum CA19-9 levels were significantly decreased (P<0.05). The analysis of serum CA19-9 levels has high value for the differential diagnosis, curative effect observation and prognosis evaluation of pancreatic cancer.