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目的探讨血清降钙素原(PCT)对慢性阻塞性肺疾病急性加重期(AECOPD)患者的诊断价值。方法 80例AECOPD患者进行痰细菌定量培养、血清PCT测定。结果 80例患者31例痰培养出致病菌。细菌感染组(A组)患者血清中PCT水平为(3.25±1.05)μg/L,无细菌感染组(B组)患者血清中PCT水平为(0.25±0.26)μg/L,两组差异有统计学意义(P<0.01)。结论血清学PCT指标能早期正确鉴别细菌感染及非细菌感染AECOPD患者,血清PCT水平高低可作为是否使用抗菌药物的参考依据。
Objective To investigate the diagnostic value of serum procalcitonin (PCT) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods 80 cases of AECOPD patients were sputum bacterial culture, serum PCT determination. Results In 80 patients, 31 cases of sputum produced pathogenic bacteria. The serum PCT level was (3.25 ± 1.05) μg / L in patients with bacterial infection (group A), and (0.25 ± 0.26) μg / L in patients without bacterial infection (group B) Significance (P <0.01). Conclusions Serological PCT can accurately identify bacterial infection and non-bacterial infection in patients with AECOPD at early stage. The level of serum PCT can be used as a reference for the use of antimicrobial agents.