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本文应用胸腺因子D加化疗药物治疗复治肺结核30例,并以单纯化疗药物治疗组25例作对照,以观察胸腺因子D对肺结核病人免疫功能的影响及辅助治疗的疗效。结果显示,胸腺因子D加化疗组治疗3个月后,OKT＋3、OKT＋4、OKT＋8细胞百分率。T＋4／T＋8及NK细胞活性均显著升高,各种免疫球蛋白水平也趋于恢复,与单纯化疗组相比有显著性差异(P＜0．01～0．05)。痰菌阴转率(59．3％)也明显高于对照组(44．0％)。提示胸腺因子D辅助治疗肺结核在提高细胞免疫功能方面有一定价值。
In this paper, Thymus D plus chemotherapy drugs in the treatment of re-treatment of tuberculosis in 30 cases, and the chemotherapy alone group of 25 cases as a control to observe the effect of thymus factor D on immune function in patients with pulmonary tuberculosis and adjuvant therapy. The results showed that the percentage of OKT + 3, OKT + 4, OKT + 8 cells in thymus D plus chemotherapy group after 3 months of treatment. T + 4 / T +8 and NK cell activity were significantly increased, a variety of immunoglobulin levels also tend to recover, compared with the chemotherapy group was significantly different (P <0.01 ~ 0.05). Phlegm negative conversion rate (59.3%) was also significantly higher than the control group (44.0%). Tip thymus D adjuvant treatment of pulmonary tuberculosis in improving cellular immune function has some value.