论文部分内容阅读
目的：阐述无复发生存率（ＦＬＦ）和无远处转移生存率（ＦＤＭ）在肿瘤预后研究中的重要性和必要性。方法：４１１例初次放射治疗的鼻咽癌病例资料纳入研究，以生存率、无复发生存率和无远处转移生存率为预后指标，通过ＣＯＸ比例风险模型，分析比较影响鼻咽癌生存、复发和远处转移的因素。结果：与生存有关的因素为性别，’９２分期，Ｎ分期，颈部射线；放射治疗后鼻咽肿瘤残留与鼻咽复发存在密切关系，与远处转移密切相关的因素是Ｎ分期。结论：只有应用无复发生存率（ＦＬＦ）和无远处转移生存率（ＦＤＭ）为指标，才能明确影响肿瘤复发的因素和转移的因素，这两个指标在评价治疗措施和肿瘤分期研究中均有意义。
Objective: To demonstrate the importance and necessity of non-recurrence (FLF) and distant metastasis-free survival (FDM) in the prognosis of cancer. Methods: The data of 411 cases of primary nasopharyngeal carcinoma treated with radiotherapy were included in the study. Survival, recurrence-free survival and distant metastasis-free survival were used as prognostic indicators. The COX proportional hazards model was used to analyze the influence of nasopharyngeal carcinoma survival and relapse And distant metastasis factors. Results: Survival related factors were sex, ’92 staging, N staging and neck radiography. There was a close relationship between nasopharyngeal tumor remnant and nasopharyngeal recurrence after radiotherapy, and the factor closely related to distant metastasis was N staging. CONCLUSION: Only the application of recurrence-free survival (FLF) and distant metastasis-free survival (FDM) as an index can clearly affect the factors of tumor recurrence and metastasis, both of which are used in the evaluation of treatment measures and tumor staging Significant.