通过对325例视网膜母细胞瘤(Rb)患者的随访和分析,其中56例视神经断端有Rb细胞残留(阳性)和269例视神经断端无Rb细胞残留(阴性)。两组经眼球摘除加放射治疗(放疗)或仅眼球摘除两种不同治疗,5a以上存活率比较差别无意义。而56例视神经断端阳性病例,放疗对抑制局部Rb复发是有效的,显示差别有显著意义。对估计眶内有Rb细胞残留者加用放疗,否则就不必以放疗作为常规治疗方法,以免因放疗造成后患。 Through follow-up and analysis of 325 patients with retinoblastoma (Rb), Rb cell residues (positive) were found in 56 cases of optic nerve stenosis and Rb cells remained (negative) in 269 cases of optic nerve stenosis. The two groups were treated by enucleation plus radiotherapy (radiotherapy) or enucleation alone. There was no significant difference in survival rate over 5 years. In 56 patients with positive optic nerve stenosis, radiotherapy was effective in inhibiting local recurrence of Rb, indicating a significant difference. It is estimated that there are residual Rb cell residues in the orbital with radiotherapy. Otherwise, it is not necessary to use radiotherapy as a conventional treatment method to avoid the occurrence of future troubles due to radiotherapy.