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目的:探讨妊娠合并血小板减少的原因及围生期处理方法。方法:回顾性分析2005年10月--2011年4月产科分娩的136例妊娠合并血小板减少患者临床资料。结果:妊娠合并血小板减少的主要原因有妊娠相关性血小板减少症(PAT)79例(58.09%)、妊娠期高血压疾病(PIH)21例(15.44%)、特发性血小板减少性紫癜(ITP)18例(13.24%)、妊娠期肝内胆汁瘀积症(ICP)16例(11.76%);阴道分娩52例,剖宫产84例;产后出血16例,产褥感染1例。结论:多种原因可以导致妊娠妇女血小板减少,PAT是最常见类型。治疗采用针对病因治疗的基础上给予糖皮质激素、丙种球蛋白、输血小板等综合治疗。分娩方式视血小板多少及有无产科指征而定。
Objective: To investigate the causes of pregnancy associated with thrombocytopenia and perinatal treatment. Methods: The clinical data of 136 pregnant women with thrombocytopenia during obstetric delivery from October 2005 to April 2011 were retrospectively analyzed. Results: The main causes of thrombocytopenia in pregnancy were pregnancy-related thrombocytopenia (PAT) in 79 cases (58.09%), gestational hypertension (PIH) in 21 cases (15.44%), idiopathic thrombocytopenic purpura ) In 18 cases (13.24%), intrahepatic cholestasis of pregnancy (ICP) in 16 cases (11.76%); vaginal delivery in 52 cases, cesarean section in 84 cases; postpartum hemorrhage in 16 cases and puerperal infection in 1 case. CONCLUSIONS: Thrombocytopenia can be caused by a variety of causes in pregnant women and PAT is the most common type. Treatment for the cause of treatment based on the given glucocorticoid, gamma globulin, platelet transfusion and other comprehensive treatment. The mode of delivery depends on the number of platelets and whether obstetric indications.