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用以十二烷基硫酸钠作为主要乳化剂的水包油型乳膏基质配制盐酸苯海拉明霜时,往往使水份分离出来;而用三乙醇胺与硬脂酸生成新生皂作为乳化剂配制时,则基质软化,所以使配制发生困
An oil-in-water cream base with sodium lauryl sulfate as the primary emulsifier often results in the separation of water when it is formulated with diphenhydramine hydrochloride cream, whereas neat soap is generated as an emulsifier with triethanolamine and stearic acid When formulated, the matrix softens so the formulation is trapped