脂肪和瘦素水平与怀孕期间较高血压水平相关。该研究旨在评估健康孕妇妊娠头3月时的血清脂质和瘦素水平与怀孕期间血压纵向变化的关系。方法:纳入巴西里约热内卢一个公共医疗保健中心的孕妇队列,进行前瞻性研究,获取≤13、20~26和30~36周孕龄时的收缩压和舒张压资料作为因变量;收集≤13周孕龄时的血清脂质和瘦素水平作为自变量;采用纵 Fat and leptin levels are associated with higher blood pressure levels during pregnancy. The aim of the study was to assess the relationship between serum lipid and leptin levels in the first trimester of pregnancy and the longitudinal changes in blood pressure during pregnancy in healthy pregnant women. Methods: A prospective cohort was included in a cohort of pregnant women at a public health center in Rio de Janeiro, Brazil. Systolic and diastolic blood pressure were obtained at ≤13, 20-26, and 30-36 weeks of gestation as dependent variables. Serum lipid and leptin levels at age were used as independent variables;