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Indomethacin farnesil(IF)由脂溶性法呢醇与吲哚美辛经酯比形成。口服后.IF以原形药物被吸收.大部分以原形药物出现于血中.一部分转运至炎症部位转化成活性形式.即吲哚美辛.吲哚美辛可抑制环加氧酶·减少前列腺素的合成·故具抗炎镇痛作用。IF临床上主要用于治疗类风湿性关节炎、骨关节炎、腰痛、肱肩胛关节周围炎及颈肩臂综合征等。IF成人常用
Indomethacin farnesil (IF) is formed by the ester ratio of a fat-soluble farnesol to indomethacin. After oral administration, IF is absorbed by the prototype drug, most of which appears in the blood as a prototype drug, and is partly transported to the site of inflammation for conversion to the active form, ie indomethacin indomethacin inhibits cyclooxygenase and reduces prostaglandin The synthesis of · so anti-inflammatory analgesic effect. IF is mainly used for clinical treatment of rheumatoid arthritis, osteoarthritis, back pain, brachial scapular periarthritis and neck and shoulder syndrome. IF adult commonly used