论文部分内容阅读
目的探讨黄芪注射液对急性白血病化疗患儿造血和免疫功能的影响。方法急性白血病患儿63例随机分为治疗组31例和对照组32例,治疗组在化疗同时给予黄芪注射液0.5～1.0mL/(kg.d),共30d,对照组单用化疗,2组其他支持治疗相同。观察2组化疗后缓解率,化疗前、后血常规、T淋巴细胞亚群和自然杀伤细胞水平。结果化疗后治疗组外周血血小板计数、血红蛋白、T细胞亚群水平高于对照组(P<0.05);缓解率与对照组比较差异无统计学意义(P>0.05);化疗后2组T细胞亚群水平明显高于化疗前(P<0.05);治疗组抗生素使用天数明显少于对照组(P<0.05)。结论黄芪注射液可减轻化疗对急性白血病患儿骨髓造血功能的抑制,促进造血功能恢复,提高细胞免疫功能。
Objective To investigate the effect of astragalus injection on hematopoietic and immune function in children with acute leukemia chemotherapy. Methods 63 children with acute leukemia were randomly divided into treatment group (n = 31) and control group (n = 32). The treatment group received Astragalus Injection 0.5-1.0 mL / (kg.d) for 30 days, while the control group received chemotherapy alone. The same group of other supportive treatment. The remission rate, the blood routine, the T lymphocyte subsets and the natural killer cell level before and after chemotherapy were observed in the two groups. Results After chemotherapy, the levels of peripheral blood platelet count, hemoglobin and T lymphocyte subsets in the treatment group were significantly higher than those in the control group (P <0.05). There was no significant difference in the remission rate between the treatment group and the control group (P> 0.05) The level of antibiotics in the treatment group was significantly less than that in the control group (P <0.05). Conclusion Astragalus injection can reduce the inhibition of hematopoietic function of bone marrow in children with acute leukemia by chemotherapy and promote the recovery of hematopoietic function and improve the cellular immune function.