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目的 评价胸膜活检组织行聚合酶链反应(PCR)对结核性胸膜炎的诊断价值。方法 PCR检测65例胸膜活检组织中结核分枝杆菌DNA,并与胸水检测及胸膜活检组织病检对比。结果 胸膜活检组织PCR阳性率831%,胸水PCR阳性率为631%,胸膜活检组织病检阳性率为60.0%。前者较后两者更敏感。结论 胸膜活检组织PCR检测对结核性胸膜炎有较高的诊断价值。
Objective To evaluate the diagnostic value of polymerase chain reaction (PCR) in pleural biopsy for tuberculous pleurisy. Methods PCR was used to detect the DNA of Mycobacterium tuberculosis in 65 cases of pleural biopsy and compared with pleural effusion and pleural biopsy. Results The positive rate of PCR in pleural biopsy was 831%, the positive rate of PCR in pleural effusion was 631%, and the positive rate of pleural biopsy was 60.0%. The former is more sensitive than the latter two. Conclusion pleural biopsy PCR detection of tuberculous pleurisy have a higher diagnostic value.