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通过测定３０例正常孕产妇和６４例妊高征患者的血清尿酸（ＵＡ）、肌酐（Ｃｒ）和尿素氮（ＢＵＮ）的水平，以探讨尿酸对妊高征围产期结局的影响。结果表明：妊高征患者血清尿酸含量明显高于正常妊娠（Ｐ＜００１），而妊高征的围产儿病死率明显高于正常妊娠对照组（Ｐ＜００１），且重度妊高征患者较轻度妊高征产妇增加显著（Ｐ＜００１～００５）。认为妊高征患者血清尿酸的变化不仅可作为临床监测指标，而且对妊高征的诊断和治疗均具有参考价值
The levels of serum uric acid (UA), creatinine (Cr) and blood urea nitrogen (BUN) were measured in 30 normal pregnant women and 64 PIH patients to investigate the effect of uric acid on perinatal outcome of PIH. The results showed that serum uric acid levels in patients with PIH were significantly higher than those in normal pregnancies (P <001), but those in PIH were significantly higher than those in normal controls (P <001) Hypertension patients with mild PIH increased significantly (P <0 01 ~ 0 05). It is considered that the changes of serum uric acid in patients with PIH can not only be used as clinical monitoring indicators, but also have reference value for the diagnosis and treatment of PIH