目前肝素效价测定方法有兔全血法(中国药典),羊血浆法(美国药典)。其中羊血浆法操作简便、结果也比较准确。我国各药厂测定肝素效价均采用羊血浆法,但羊血浆来源紧张,鉴于此,曾有人按美国药典方法用猪血浆代替羊血浆进行测定,由于目前对猪血浆的制备和使用尚不尽完善,因此我们对此进行了一些实验。一、实验材料与实验方法 1.实验材料 Current heparin titer rabbit whole blood method (Chinese Pharmacopoeia), sheep plasma method (US Pharmacopoeia). One of the sheep plasma method is simple, the results are more accurate. In our country, all the pharmaceutical companies measured the heparin titer by using the sheep plasma method, but the sheep plasma source was tight. In view of this, some people used the method of the US Pharmacopoeia instead of the sheep plasma to determine the pig plasma, because the preparation and use of the pig plasma is not yet complete Perfect, so we have some experiments on this. First, the experimental materials and experimental methods 1. Experimental materials