本文对38例子宫内膜癌患者在上镭锭和子宫切除前,肌注17α-羟基-黄体酮己酸酯,其复发率为10.5%,而44例对照组的复发率为20.5%。子宫内膜癌病人经长期孕激素治疗后,可减少30—35%的复发与转移(Kister和Griffiths,1968)。但孕激素用在未经治疗的子宫内膜癌的疗效报道甚少。具有代表性的是大剂量胃肠道外注射孕激素时可促使肿瘤组织多呈良性表现,并使高度分化的癌肿常有分泌的改变(Varga和Henriksen, In this study, 38 patients with endometrial cancer were treated with 17α-hydroxy-progesterone caproate intramuscularly before radiotherapy and hysterectomy. The recurrence rate was 10.5%, while the recurrence rate was 44.5% in 20 cases. Endometrial cancer patients after long-term progestin treatment, can reduce 30-35% of the recurrence and metastasis (Kister and Griffiths, 1968). However, the efficacy of progestin used in untreated endometrial cancer is poorly reported. Typically, high-dose parenteral progesterone promotes benign tumor manifestations and often secretes changes in highly differentiated cancers (Varga and Henriksen,