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肽YY(PYY)是从肠粘膜提取的一种肠肽,它可抑制胰腺外分泌和胃酸分泌。本研究旨在确定PYY在体内外对静态和经缩胆囊素(CCK)刺激后胆囊收缩是否有作用,以及在体外对Oddi括约肌张力的影响。材料与方法:(1)体内研究:犬5只,实验前3周将压力转换器植入胆囊中部浆膜面,导线从右肋缘下引出备用。
Peptide YY (PYY) is a type of intestinal peptide extracted from intestinal mucosa that inhibits pancreatic exocrine and gastric acid secretion. The aim of this study was to determine whether PYY has an effect on the contraction of the gallbladder after static and cholecystokinin (CCK) stimulation both in vitro and in vivo as well as on the sphincter of Oddi in vitro. MATERIALS AND METHODS: (1) In vivo study: 5 dogs were implanted with pressure transducers into serosal surface in the middle of gallbladder 3 weeks before the experiment. Leads were led out from right rib margin.