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目的研究南郑县大骨节病防治效果,为控制大骨节病提供依据。方法分别于1989、1999、2009年对南郑县3个监测点进行大骨节病普查。结果 1999年比1989年总检出率下降了15.01个百分点,平均患病率下降了9.12个百分点,差异均极显著(P<0.001);2009年比1999年总检出率降了11.61个百分点,平均患病率下降了6.44个百分点,差异均极显著(P<0.001);2009年比1989年总检出率下降了26.62个百分点,平均患病率下降了15.56个百分点,差异均极显著(P<0.001)。6~13岁儿童大骨节病X线检出率在1989年、1999年、2009年分别为33.93%、8.53%、1.18%,差异极显著(P<0.001)。结论南郑县的大骨节病明显减少,防治效果显著,防治措施有效。应持续落实此类措施,控制大骨节病。
Objective To study the effect of prevention and treatment of Kashin-Beck disease in Nanzheng County and to provide basis for the control of Kashin-Beck disease. Methods The general survey of Kaschin-Beck disease was conducted on three monitoring sites in Nanzheng County in 1989, 1999 and 2009 respectively. Results In 1999, the overall prevalence rate dropped by 15.01 percentage points from 1989, and the average prevalence rate dropped by 9.12 percentage points (P <0.001). In 2009, the overall detection rate dropped by 11.61 percentage points , The average prevalence rate decreased 6.44 percentage points, the difference was extremely significant (P <0.001); in 2009 compared with 1989, the total detection rate decreased by 26.62 percentage points, the average prevalence decreased by 15.56 percentage points, the difference was significant (P <0.001). The detection rate of Kashin-Beck disease in children aged 6 ~ 13 years was 33.93%, 8.53% and 1.18% respectively in 1989, 1999 and 2009, the difference was significant (P <0.001). Conclusion Kashin-Beck disease is significantly reduced in Nanzheng County, with significant prevention and treatment effects and effective prevention and treatment measures. Such measures should be continuously implemented to control Kashin-Beck disease.