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目的通过分析慢性肺原性心脏病并发多脏器功能障碍综合征的临床特点,分析其发病的主要原因,危重因素及转归。方法选择108例肺心病患者,42例符合多脏器功能障碍综合征的诊断,给予有效抗炎等治疗,并根据各受累及器官系统给予相应治疗。结果 42例并发2个以上器官衰竭,其中呼吸衰竭40例,心力衰竭18例,中枢神经系统功能衰竭15例,肾功能衰竭10例,肝功能衰竭14例,胃肠功能衰竭8例,凝血系统衰竭4例;经救治无效死亡11例,多为60岁以上患者,死亡率与受累及脏器数和病程呈正相关。结论肺部感染及长期低灌流量是肺心病急性发作及导致并发多脏器功能障碍综合征的主要原因。肺心病并发多脏器功能障碍综合征死亡率高低,主要取决于受累的器官系统及其损伤持续时间,年老也是重要因素。
Objective To analyze the clinical features of chronic pulmonary heart disease complicated with multiple organ dysfunction syndrome and to analyze its main causes, critical factors and prognosis. Methods A total of 108 cases of patients with cor pulmonale were selected and 42 cases were diagnosed as having multiple organ dysfunction syndrome. The patients were given effective anti-inflammatory treatment and the corresponding treatment was given according to the involved organ systems. Results Forty-two patients developed organ failure, including 40 cases of respiratory failure, 18 cases of heart failure, 15 cases of central nervous system failure, 10 cases of renal failure, 14 cases of liver failure, 8 cases of gastrointestinal failure, 8 cases of coagulation system Failure in 4 cases; after treatment ineffective death in 11 cases, mostly in patients over the age of 60, the mortality and involvement and organ number and duration of a positive correlation. Conclusion Pulmonary infection and long-term hypoperfusion are the main causes of acute pulmonary heart disease and multiple organ dysfunction syndrome. Pulmonary heart disease complicated by multiple organ dysfunction syndrome, the level of mortality, mainly depends on the affected organ system and the duration of injury, age is also an important factor.