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对生物可吸收聚-DL/L-丙交酯(30DL/70L)体系进行了静电纺丝。研究了聚-DL/L-丙交酯(30DL/70L)的浓度,加料速度,电压,喷头与接收体之间的距离等因素对纤维形态的影响,制备出纳米纤维膜,并用扫描电镜(SEM)等对纤维膜进行表征。结果表明,电纺溶液浓度和溶剂对纤维直径影响比较明显,减小电纺溶液浓度和采用复合溶剂CHCl3/DMF可得到更细的纳米纤维;一定范围内适当的增加电压、减小距离和减小加料速度有利于减小纤维直径。在聚-DL/L-丙交酯(30DL/70L)浓度为5g/100mL溶剂、加料速度1mL/h、喷头与接收体之间的距离6cm、电压15kV电纺条件下,可制备直径50nm左右的聚-DL/L-丙交酯(30DL/70L)纳米纤维膜。
The bioabsorbable poly-DL / L-lactide (30DL / 70L) system was electrospun. The effects of the concentration of poly-DL / L-lactide (30DL / 70L), feeding rate, voltage and the distance between the showerhead and the receiver on the morphology of the fibers were studied to prepare nanofibrous membranes. Scanning electron microscopy SEM) to characterize the fiber membrane. The results show that the concentration of electrospinning solution and the influence of solvent on the fiber diameter are obvious. Decreasing the concentration of electrospinning solution and using compound solvent CHCl3 / DMF can obtain finer nanofibers; within a certain range, increasing the voltage, reducing the distance and decreasing Small feed rates help to reduce the fiber diameter. In the poly-DL / L-lactide (30DL / 70L) concentration of 5g / 100mL solvent, the feed rate of 1mL / h, the distance between the nozzle and the receiver 6cm, voltage 15kV electrospinning conditions can be prepared about 50nm in diameter Poly-DL / L-lactide (30DL / 70L) nanofiber membrane.