慢性肾脏疾病(CKD)是成人常见疾病之一,而CKD易发生室性心律失常,此与CKD的分期、动脉粥样硬化、左室肥厚、电解质紊乱以及血液透析等密切相关。抗心律失常药物(AADs)在治疗心律失常患者时存在着致心律失常风险,尤其对于CKD患者更加明显,应注意AADs通过肾脏代谢和过滤的问题。 Chronic kidney disease (CKD) is one of the common diseases in adults, and CKD is prone to ventricular arrhythmia, which is closely related to CKD staging, atherosclerosis, left ventricular hypertrophy, electrolyte imbalance and hemodialysis. Antiarrhythmic drugs (AADs) are at risk for arrhythmias in the treatment of patients with arrhythmias, especially in patients with CKD and attention should be paid to the problem of AADs passing through the kidneys’ metabolism and filtration.