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帕金森病 (PD)是一种中老年人锥体外系统的变性疾病。从英国学者 James Parkinson(1817年 )首次对 PD进行描述至今已近两个世纪 ,目前对 PD病因的认识仍不清楚。但已有越来越多的研究支持环境毒物或内源性毒物加速了多巴胺神经元的丧失的观点 ,当纹状体中多巴胺 (DA )减少到维
Parkinson’s disease (PD) is a degenerative disease of the extrapyramidal system in the elderly. It has been almost two centuries since the British scholar James Parkinson (1817) described PD for the first time and the current understanding of the cause of PD remains unclear. However, more and more studies have supported the viewpoint that environmental toxicants or endogenous toxicants accelerate the loss of dopamine neurons. When striatum reduces dopamine (DA) to the dimension